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We demonstrated that 100 nmol/l calphostin C and 50 mol/l TPPO each reduced the triagonist-induced GSIS increase by about 60% in primary islets (Fig
Plasminogen activator inhibitor 1, transforming growth factor-beta1, and BMI are closely associated in human adipose tissue during morbid obesity

A large tirzepatide trial pushed average loss even higher, which explains why response differences now matter so much

Epub 2023 Nov 7
