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Summary: Retatrutide, an investigational triple receptor agonist, may produce early appetite changes within two to four weeks, with measurable weight loss typically emerging between weeks four and twelve based on phase 2 trial data

Do not stop retatrutide solely because of hair shedding

Some GLP-1 medications (specifically liraglutide, semaglutide and dulaglutide) have demonstrated cardiovascular benefits in certain patient populations with type 2 diabetes

Pharmaceutical GLP-1 agonistssuch as semaglutidehave become popular, but they are synthetic, require prescriptions, and may carry side effects with long-term use