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2 What perhaps is most striking about this article is the degree of risk reduction of AMD found in patients taking GLP-1 drugs, which was found to be greater than 80% at five years and increased with the later time points up to 10 years, compared with other weight loss drugs, the authors wrote in their commentary in JAMA Ophthalmology

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While an attention-getting 2025 study suggested that this rebound worsened some pregnancy outcomes, the risks and benefits are still poorly understood, Dr

GLP-1 analogs (exendin-4) can also improve hepatic steatosis [35] in ob/ob mice both in vivo and in vitro [36]