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Regulatory context for compounded GLP-1 medications: The FDA placed semaglutide and tirzepatide on the national drug shortage list during peak GLP-1 demand, which historically supported expanded compounding under sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act
Identifying the compounds and pathways that stimulate endogenous GLP-1 secretion remains a critical step in advancing this therapeutic avenue
