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GLP-1 receptor agonists stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning they promote insulin release only when blood glucose levels are elevated

Bonaca MP, Catarig AM, Houlind K, et al

After certain GLP-1 receptor agonist drugs such as Ozempic and Wegovy were placed on the FDA drug shortage list, specialized pharmacies began compounding semaglutide and other similar peptide-based drugs for patients seeking to use them for weight loss purposes

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