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You need the semaglutide vial, an unused insulin syringe (typically 0.5 mL or 1 mL capacity depending on your dose), an alcohol swab, and a sharps disposal container

Yes, while its not included in the official side effect profile, many patients say they feel colder than before starting treatment

To reduce bruising, apply gentle pressure (do not rub) for 10-15 seconds after injection, ice the site if needed, and be aware that blood thinners and supplements like fish oil increase bruising tendency

Cardiovascular outcomes trials have demonstrated reduced rates of major adverse cardiovascular events in high-risk patients treated with liraglutide (LEADER trial) and semaglutide (SUSTAIN-6 trial)