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Studies using hippocampal tissue obtained from patients with temporal lobe epilepsy and a mouse model of pilocarpine-induced epilepsy have shown that decreased GLP-1R expression in hippocampal microglia correlates with increased cytokine release and astrocyte activation [73]

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These agents help reduce appetite and delay gastric emptying, leading to reduced food intake useful for people with obesity

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Additionally, the effects of liraglutide were partially blocked by exendin-(9-39) (Fig

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RDs also can advocate for the safe and proper use of weight management medications in tandem with promoting the critical roles of healthful eating, lifestyle modifications, and medication adherence

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