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Strong appetite suppression often works against those conditions

Given our findings, future research with Dandelion data will focus on (i) investigating the heterogeneity in treatment response to GLP-1s, (ii) modeling predictors of patient responsiveness, and (iii) analyzing unstructured clinical data to understand the impact of GLP-1s on measures beyond weight loss and HbA1c (e.g., loss or preservation of lean body mass)

SURMOUNT-1 (72-week randomized study, adults without diabetes): tirzepatide produced an average loss of 15.0% (5 mg dose), 19.5% (10 mg dose), and 20.9% (15 mg dose) of body weight, versus 3.1% with placebo, under a similar lifestyle-intervention protocol

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