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Patients typically see measurable fat loss within 4-6 weeks, though initial weight changes include water loss and reduced food volume in the digestive tract

Trial periods of two to four weeks often reveal which format your body prefers before committing to longer-term treatment
doi: 10.2337/diabetes.53.9.2492 [DOI] [PubMed] [Google Scholar] 93

Setting Realistic Expectations for Semaglutide Timelines Weight loss typically becomes visible after 48 weeks of consistent dosing, with meaningful progress (510% of body weight) expected by 1216 weeks
