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Description
Hypocretins (orexins) regulate serotonin neurons in the dorsal raphe nucleus by excitatory direct and inhibitory indirect actions
The highest approved dose of oral semaglutide (14 mg/day) is currently indicated only for treating T2DM as an adjunct to diet and exercise
Patients with established cardiovascular disease Those with previous myocardial infarction, stroke, or peripheral arterial disease may benefit from the cardioprotective effects of certain GLP-1 receptor agonists, which include modest blood pressure reductions alongside other cardiovascular benefits
So the drug is there, but its full effect isnt
