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Kline is a board-certified family medicine physician and co-founder of Trinity Family Medicine

Quick Answer: Weight gain on tirzepatide can occur due to fluid retention, metabolic adaptation, inadequate dosing, medication interactions, lifestyle factors, or underlying medical conditions that counteract the medication's appetite-suppressing effects

The Centers for Disease Control and Prevention (CDC) reports that U.S

Staying properly hydrated with small, consistent sips of fluids helps prevent worsening stomach discomfort
