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This three-day sample menu includes balanced meals and 1,300-1,500 calories per day
Phase 2 trials have also highlighted other possible side effects, like injection site reactions
In contrast to common obesity, where cardiovascular risk reduction drives intervention, the main rationale for treatment in MC4R -deficient patients shifts toward alleviating mechanical complications (e.g., sleep apnea, osteoarthritis), preventing diabetes (hyperinsulinemia is common despite relative euglycemia), and improving quality of life [30]
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