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No extreme dieting required

The patient should continue semaglutide while initiating first-line RLS treatment with alpha-2-delta ligands (gabapentin, gabapentin enacarbil, or pregabalin...

The treatment of this condition requires dietary changes, but severe cases require drug therapy

Additionally, GLP-1 analogs reduced energy expenditure, with only tirzepatide showing a significant decrease in the respiratory quotient (RQ) in MC4R KO mice