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Hormone delivery method optimization Before starting a GLP-1 medication, evaluate your HRT delivery method: If you are on oral HRT: Talk to your provider about switching to transdermal delivery (patches or gels) for estrogen, and either a Mirena IUD or transvaginal delivery for progesterone

The medicine, as she writes in the book, has "opened up the aperture of adventure and possibility and new experiences." "We want to be able to live out the truest, purest, highest possibility of ourselves as human beings," Winfrey says in the closing chapter of the book

All eight trials were designed as noninferiority trials

The relationship between GLP-1 receptor agonists and hair loss remains an area of ongoing investigation