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GLP-1RAs mitigate these adverse impacts by enhancing fatty acid oxidation via the Creb5/NR4a1 signaling axis, thereby reducing mitochondrial damage, lipid accumulation, and ATP deficiency (77, 78, 83)
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RNA immunoprecipitation (IP) and quantitative PCR JK5366 and JK5574 were raised at 15C until they developed germline tumors as young adults (see tumor assay above)
