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A phase 3 trial published in 2024 showed tirzepatide cut AHI scores substantially and improved weight, blood pressure, and systemic inflammation

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GLP-1 medications are initiated at low doses and gradually increased to minimise gastrointestinal side effects such as nausea and vomiting

The complex interaction of factors such as insulin resistance, glucotoxicity and lipotoxicity contribute to the pathogenesis and coexistence of diabetes and metabolic-dysfunction associated steatotic liver disease (MASLD) in a reciprocal process of exacerbating the underlying conditions [9]