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These modifications can influence how the drug behaves in the body, including its stability and activity

Significant weight loss from GLP-1 therapy may require levothyroxine dose adjustments, as thyroid hormone needs are partially determined by body weight

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A patient who can afford and tolerate semaglutide for two years will have better outcomes than a patient who starts tirzepatide, hits financial or side effect barriers at month four, and discontinues
