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Description
GLP-1 (GLP-1R)
However, conventional weight loss interventions have yielded ...

Conclusions Hypomorphic PAM T2D-risk alleles reduce amidating enzyme activity, elevate circulating GLP-1 levels, and impair GLP-1 post-receptor signaling, culminating in a selective and clinically meaningful reduction in GLP-1RA efficacy

GLP-1 (Glucagon like peptide-1 receptor agonists)
