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Weighing risk versus benefit is key here, but both Levy and Salas-Whalen pointed out that untreated obesity carries risks and shouldn't be overlooked
(1993) Renal catabolism of truncated glucagon-like peptide 1

It may also be necessary to consult a doctor for complex medical conditions that require more intensive treatment

(Migraines are considered chronic when someone has a headache on 15 or more days a month for at least three months.) The researchers divided the participants into two groups: Those who started taking a GLP-1 medication for another condition (such as type 2 diabetes or obesity) within a year of being diagnosed with chronic migraines, and those who started taking topiramate (a prescription medication used to prevent migraine headaches) during the same period
