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This year, Blue Cross Blue Shield of Massachusetts announced that it would stop covering GLP-1s for obesity, saying the drugs costs were driving insurance premiums too high

That means the weight loss results reported in those trials reflect a combination of the medication and behavioral changes, not the medication alone

Jared Dashevsky, MD, is an internal medicine physician and incoming pulmonary and critical care fellow at Mount Sinai, and the founder of Healthcare Huddle a newsletter read by over 30,000 physicians and healthcare professionals

The GLP-1 receptor is expressed on the surface of cells across many different tissues, including the pancreas, intestines, liver, central and autonomic nervous systems, immune system, heart, and muscle