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The study concluded that in patients with obesity-related heart failure and T2DM with preserved ejection fraction, semaglutide treatment resulted in significantly greater reductions in heart failure-related symptoms and physical limitations, as well as more pronounced weight loss at one year compared to placebo
In cases where pancreatitis is suspected, discontinuation of GLP-1 RA and appropriate medical intervention are recommended according to the risks and benefits for each patient [65]

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