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Semaglutide 2.4 mg for the Treatment of Obesity: key Elements of the STEP trials 1 to 5

The molecule is a 39-amino-acid peptide that acts as a dual agonist, activating both the glucose-dependent insulinotropic polypeptide (GIP) receptor and the glucagon-like peptide-1 (GLP-1) receptor simultaneously

However, the sensitivity analysis conducted with the results of the treatmentregimen estimand in the full population of both trials supported the results of the primary analysis