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Conclusion This analysis of IPD from three large RCTs assessing semaglutide treatment demonstrated a significant reduction in SBP that is comparable in normotensive and hypertensive participants

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Drug Makers Ignore More Significant Evidence in Trials The International Journal of Clinical Pharmacy highlighted a concerning association between semaglutide and adverse psychiatric events. Between January 2021 and May 2023, databases recorded 481 psychiatric events associated with GLP-1 medications and similar drugs, including 9 deaths and 11 life-threatening outcomes. Poison control centers reported nearly 3,000 calls involving semaglutide in less than a year

By protecting the optic nerve, semaglutide could, in theory, help slow down the progression of glaucoma