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Pharmaceutical Manufacturing and Supply Chain Challenges With rising demand for obesity and diabetes drugs, manufacturers face significant challenges: API shortages due to limited global supply

Targeting mitochondrial quality control for diabetic cardiomyopathy: therapeutic potential of hypoglycemic drugs

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As with all GLP-1 receptor agonists, there are class-level safety considerations to be aware of, based on UK Summary of Product Characteristics (SmPC) for approved agents such as semaglutide (Wegovy): Pancreatitis : If pancreatitis is suspected indicated by severe, persistent abdominal pain, which may radiate to the back treatment should be stopped immediately and urgent medical assessment sought