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Table of Contents Chapter 1

Geniposide, a major iridoid glycoside of Gardenia jasminoides and a GLP-1R agonist, dose-dependently reduced formalin-induced pain in rats without generating antinociceptive tolerance [40]

If approved, a biweekly shot could offer an alternative to once-weekly GLP-1 injections for the needle-averse

It is important to understand that the key players evaluating their novel therapies in the pivotal and confirmatory trials should remain vigilant when selecting appropriate comparators to stand the greatest chance of a positive opinion from regulatory bodies, leading to approval, smooth launch, and rapid uptake