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Gastrointestinal side effectsparticularly nauseamay be more pronounced than during initial treatment if restarting at a higher dose
24.2% at 48 weeks in Phase 2 Tirzepatide : Up to 20.9% body weight reduction (SURMOUNT trials) Advantage : Retatrutide Regulatory Status# Retatrutide : Phase 1-3 clinical trials
That said, clinical studies included individuals with type 2 diabetes and both overweight and obese people (depending on the specific clinical trial)
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