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Study 5 enrolled 234 patients who were unable or unwilling to use Positive Airway Pressure (PAP) therapy and Study 6 enrolled 235 patients who were on PAP therapy

A 2016 study detailed 47 obesity drugs withdrawn because of adverse drug reactions, mostly due to heart problems, addiction issues or psychiatric effects

The most common side effects are gastrointestinal, including: Nausea Diarrhea Vomiting Constipation These are dose-dependent and usually mild to moderate
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