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CVS Caremark dropped Zepbound in July 2025, affecting 200K+ patients

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Usually a result of orthopedic degeneration (arthritis), joint pain not only makes it physically difficult for people to move, it can diminish quality of life as they struggle with the psychological effects of living with chronic pain.
In contrast, no benefits on the rate of decline in glomerular filtration rate have been seen in trials of DPP-4 inhibitors, perhaps because the renal actions of DPP-4 inhibitors are primarily mediated by potentiation of SDF-1, not GLP-1
