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Despite the species differences, the FDA maintains a boxed warning for these compounds

Patients who lose the most weight on GLP-1s tend to make protein-forward food choices, stay hydrated (GLP-1s slow gastric emptying and dehydrate patients faster than they realize), prioritize sleep (sleep deprivation drives weight regain), and add some form of strength training

[DOI] [PMC free article] [PubMed] [Google Scholar] 50.A critical review of akathisia, and its possible association with suicidal behaviour
