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The GLP-1 drugs are an example of why
Zhao T, Zheng L, Feng Y, Lao M, Huang Y, Wu G

Researchers analyzed Fitbit data found that daily step counts and exercise levels dropped after people started these medications, despite successful weight loss

Weight loss was also assessed in the SCALE Sleep Apnea RCT, in which 359 non-diabetic individuals (mean age 48.5 years, mean BMI 39.1 kg/m 2 ), mostly males with untreated obstructive sleep apnea (OSA), were enrolled to investigate the effect of liraglutide on disease severity 20
