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The mechanism is obesity-specific in mice

About our expert: Oluwatosin Ajao, MD, known as Dr

These invasive gut surgical procedures, aimed to reduce absorptive surface area of the proximal GI tract, such as Roux-en-Y gastric by-pass (RYGB) or Sleeve Gastrectomy (SLG), are associated with an improved glycaemic control, weight loss, and often with complete remission from T2DM ( Despite this, the complete remittance of a great fraction of RYGB patients represents a fascinating new case-series that points at the importance of the EECs and its modulation of the whole-body metabolism (28)

Because of its role as an incretin hormone, GLP-1 receptor analogs are used as a treatment for type 2 diabetes