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[24] When women with PCOS lose weight through any means (diet, exercise, or medication), they may experience: Restoration of regular ovulation and menstrual cycles Improved hormonal balance (reduced androgens, better insulin sensitivity) Increased likelihood of spontaneous conception Because Ozempic can lead to substantial weight loss, women with PCOS taking this medication may find that their fertility improves as a secondary consequence of metabolic improvement , not due to a direct effect of the drug itself

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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist originally developed to treat type 2 diabetes, but clinical research has shown it produces significant weight loss in people with obesity

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B., & Dawson-Hughes, B

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the Division of Endocrinology, Diabetes, and Metabolism, Ohio State University, Columbus (K.D.)

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