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According to current studies, the molecular pathways involved in GLP-1RAs impact on RGCs rescue can be categorized into two groups (Figure 2)

The glucagon-like peptide 1 (GLP-1) analogue, exendin-4, decreases the rewarding value of food: A new role for mesolimbic GLP-1 receptors

Salehi M, Aulinger BA, DAlessio DA

Exenatide once-weekly improves metabolic parameters, endothelial dysfunction and carotid intima-media thickness in patients with type-2 diabetes: an 8-month prospective study