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In addition, some aspects of GLP-1 beyond weight loss, such as preclinical evidence on GLP-1 effects in directly modulating the hypothalamuspituitarygonadal axis, or the effects of GLP-1RA on clinical and biochemical expression of hyperandrogenism, still deserve a greater insight, especially in light of a possible therapeutic use in PCOS women independently of obesity

No, as of now.Retatrutide is an investigational drug,currently only available through legitimate clinical trials, with Phase 3 trials concluding in 2026

Van DerSchootA, Drysdale C, Whelan K,DimidiE. The effect offibersupplementation on chronic constipation in adults: An updated systematic review and meta-analysis of randomized controlled trials.AmJ ClinNutr.2022;116:953-969. doi:10.1093/ajcn/nqac184
