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Description
The fall in leptin concentration is a major determinant of the metabolic adaptation induced by caloric restriction independently of the changes in leptin circadian rhythms
These are unwelcome side effects considering many midlife women struggle with lower libido due to perimenopause and menopause
Starting with lower doses (5 grams or less) and gradually increasing intake can help minimize these effects
Numerous studies have shown that effective reduction in body weight, as compared to placebo
