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In contrast to studies of enzalutamide and apalutamide, darolutamide was not associated with a higher incidence of falls or fractures, hypertension, or central nervous systemrelated adverse effects when compared with placebo

Situations where magnesium citrate might be considered: Occasional constipation when preferred laxatives are unsuitable Short-term use when other approaches have been ineffective As part of a broader approach including dietary fibre and hydration It is important to recognise that magnesium citrate addresses symptoms rather than underlying causes of constipation

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Unmet clinical needs and burden of disease in hidradenitis suppurativa: real-world experience from EU5 and US