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Description
Patients with suspected cortisol disorders require specialist endocrinology referral for appropriate investigation and evidence-based treatment

Importantly, localized increases in GLP-1, such as that occur in the gut and portal vein, often have a more profound effect than systemic elevations, emphasizing the therapeutic potential of targeting regional activity rather than relying solely on systemic concentrations

Current guidelines suggest a target of 1.2 to 1.6 grams of protein per kilogram of body weight per day during active weight loss in adults

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