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Food and Drug Administration tells TODAY.com in a statement

Using synthetic derivatives of curcumin that have different stability (i.e., different propensity to form electrophilic metabolites) a correlation was observed between the rate of degradation and the ability to inhibit NF-B (18)

The process requires extensive documentation, physician appeals, and 6-8 weeks of waiting

It can be used short-term in conjunction with diet and exercise to support weight loss
