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Description
Uncontrolled studies Using weekly semaglutide, prandial insulin was discontinued in all patients, and basal insulin was discontinued in 7 out of 10 patients

A recent multicenter international phase II RCT (GOLDEN-505) in noncirrhotic biopsy-proven NASH patients showed an insignificant difference in NASH resolution without fibrosis progression between the elafibranor and placebo groups at 52 weeks of treatment

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That is their primary benefit for weight loss
