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As body weight decreases, total daily energy expenditure decreases, and the deficit that produced rapid early weight loss narrows

This adaptation represents a normal physiological response, not medication-induced harm

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PCP Channel Activation Ongoing education and familiarization of primary care providers on the efficacy and appropriate utilization of GLP-1s is critical to market access pull-through, given that a great majority of GLP-1 prescriptions originate from the PCP channel