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[DOI] [PMC free article] [PubMed] [Google Scholar] 126.Rashid R., Mir S.A., Kareem O., Ali T., Ara R., Malik A., Amin F., Bader G.N

Two studies found GLP-1s were associated with improvement in depressive symptoms and two other studies tied GLP-1s to an improvement in alcohol use disorder among people with obesity

As a drug class, the GLP-1 receptor agonists possess properties that could translate to improved renal energetics including its effects on substrate metabolism

After stratification by specific GLP-1 receptor agonist-SGLT-2 inhibitor combinations, the hazard ratios ranged from 0.64 for the liraglutide-dapagliflozin combination to 1.18 for the liraglutide-empagliflozin combination with confidence intervals overlapping each other (supplementary table E)