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Ozempic side effects are often most noticeable: during the first days or weeks of treatment after increasing the dose when restarting treatment Digestive side effects such as nausea, vomiting, diarrhea, constipation, and stomach pain are usually more common early in treatment and may improve over time

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By selectively augmenting insulin release, modulation of GLP-1R trafficking may be a viable strategy to achieve greater metabolic control in T2D without increasing the rate of unwanted side effects, such as nausea

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