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Incretin action in islets and implications for diabetes The findings that the acute insulinotropic actions of GLP-1, but not GIP, were relatively preserved in people with type 2 diabetes (T2D) (2) focused greater attention on the therapeutic potential of GLP-1, ultimately supporting multiple clinical development programs for GLP-1 receptor (GLP-1R) agonists (GLP-1RA)

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(1) At some point in their life, 1 in 10 people develops the condition

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