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The existing evidence provides a strong clue: GLP-1s not only affect the gut and metabolic centers but also modulate the brain's DMN

doi: 10.1158/1078-0432.CCR-13-0458

We evaluated effect of semaglutide on the in vivo release of dopamine metabolites (DOPAC and HVA) and gene expression of enzymes metabolising dopamine (MAOA and COMT) in male mice

Role of the glucagon-like-peptide-1 receptor in the control of energy balance
