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For less urgent concerns, patients should contact their GP or rheumatology team promptly if they experience worsening joint symptoms, new swelling, or signs of infection, as these may require assessment and treatment adjustment
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10.1016/j.bbrc.2019.06.112 46 ZhangY.CaoX.LiP.FanY.ZhangL.LiW.et al (2020)

Her acute condition ultimately required an appendectomy