glp 1 effect on kidneys GLP-1 mediated diuresis and natriuresis are blunted in heart failure and restored by selective afferent renal denervation | Cardiovascular Diabetology GLP-1 receptor agonists and next-generation
Description
More body fat means more aromatase activity, which means lower testosterone and higher estrogen in men

Common side effects include nausea and constipation, which typically diminish over time

Nat Commun 6:10062 Christiansen CB et al (2018) The impact of short-chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon

And the weight loss achieved with diet and exercise might not happen as quickly as it would with GLP-1 medications
