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After a dose-titration and dose-stable run-in period of up to 16 weeks and a 2-week placebo run-in period, patients with inadequate glycemic control (A1C 7.5% to 10.5%) were randomized to the addition of either 100 mg of sitagliptin or placebo, administered once daily
But whether that weight loss preserves your muscle depends heavily on protein prioritization
Sommers T, Mitsuhashi S, Singh P, et al
Missing injectable doses once per week is much harder than missing daily oral doses
