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DNA methylation is the process of chemically modifying DNA by the addition of a methyl group and it affects gene expression

Evidence suggests that tirzepatide may exacerbate diabetic retinopathy in some individuals, so early disclosure allows for appropriate monitoring or the consideration of alternative treatment options, if necessary (MacIsaac et al

Some individuals carry genetic predispositions that make them rapid responders to dual-action therapy, while others benefit from a slower dose escalation or may respond better to a different medication altogether

Tirzepatides dual agonism of GIP and GLP-1 receptors may underpin its superior efficacy
