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GLP-1 itself is a hormone secreted by the intestines in response to food intake, which interacts with receptors in the brain to signal satiety and reduce appetite

10.1136/gut.44.1.81 [DOI] [PMC free article] [PubMed] [Google Scholar] 5.Xu J, Xiao X, Li Y, Zheng J, Li W, Zhang Q, et al

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Inadequate Calorie Intake Over the Long-Term Now, using the section on a chronically stressed state, we can use what we know to understand what occurs when were in a caloric deficitwhether intentionally or unintentionallyfor prolonged periods