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Statistics and reproducibility The phase 2 clinical trial was powered to show a difference in proportions of 28% on primary endpoint MASH resolution and no worsening of fibrosis between once-daily semaglutide 0.4 mg (assumed 45% response) and placebo (assumed 17% response)

(2) Hyperphagia

Results may be influenced by treatment adherence, lifestyle modifications, individual metabolism, growth and development (in adolescents), underlying health conditions, and emotional wellbeing

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